; Children: A safe and effective oral dose of NAC hasn't been established.Don't give it to children unless directed to by a healthcare provider. The only form of strontium for which ADRs have ever been reported is the unnatural, drug form, strontium ranelate, which has never been approved for use in the U.S. and whose use is now severely restricted in Europe. . It would be very helpful if you could clarify. My bones have been in excellent shape now for more than 6 years (within 6 months after I started taking AlgaeCal Plus), but I continue to take a half dose (1 capsule) of Strontium Boost daily to ensure they stay healthy! How long is it safe to use at the full recommended dosage and at what dosage is it safe to use after reaching the normal levels? This is because food and some drinks can affect the way these medicines work. Hi David, Lara has forwarded her response to us. In recent years, HER2 has become an important biomarker and target of therapy for approximately 30% of breast cancer patients. Health Canada claim pending. Again, the study says nothing about strontium weakening bone structure. Now I am barely osteopenic and expect my next DXA will show I am fully in the healthy normal range. K1 has significant anti-inflammatory effects. Environ Res. Ranelic acid was claimed to be completely inert and to be completely eliminated from the body. Thank you for reaching out, Susan! Back in 2009, I wrote several medical journal articles about all this, which are still posted free access on the Longevity Medicine Review website. Strontiums effect of increasing OPG production was a key factor in the following bone-protective outcomes: greater trabecular bone volume, an increase in the number of trabecular bone cells, larger areas of the bone surface occupied by osteoid cells (osteoid is the last step before final mineralization occurs to produce fully developed new bone tissue), [all trabecular bone] an increase in bone formation rate, and fewer, smaller areas of bone in which osteoclasts were active. Happy Thanksgiving to you, too. Delighted you are finding the information in Your Bones annd here on AlgaeCals blog helpful. The citrate portion is both an alkalinizer (so helps prevent an acidic body pH, which promotes calcium withdrawal from bone / bone loss) and is also used in the Krebs cycle (a key part of the energy production cycle in our cells). They both contain sodium, but when you connect that sodium molecule to another molecule, its actions are completely different! How does it compare to the AlgaeCal that you recommend? Many cellular processes do not happen effectively in an acidic environment, and furthermore, an acidic pH (called metabolic acidosis) over activates osteoclasts and promotes bone loss. Yes, I take the full dose (2 capsules twice daily) of AlgaeCal Plus, but now that my bones are in great shape, I only take a half dose (1 capsule) of Strontium Boost. Please call us at 1-800-820-0184 if you have any questions, and any one of our Bone Health Consultants would be so happy to help , Hi Lara, I have read articles on the internet that say Strontium Citrate can cause hair loss. I hope you will give AlgaeCal a try when you need to reorder you calcium supps. My apologies, but I dont have time right now to repeat the full discussion, but it and all the references can be found on AlgaeCals blog. Many factors in our current environment prevent us from getting sufficient iodine for optimal thyroid function. I was wondering what your opinion on giving dogs canned sardines in water is. If you havent read it, please consider doing so. 16/04/2012 18:14. When a combined amino acid compound has been introduced to your NAC arrangement, please also consume it when your stomach is empty, just at another moment of the day than the NAC plan. You can definitely take your strontium first thing in the morning! This supplement supports healthy osteoblast differentiation osteoblast collagen formation and balanced osteoclast activity; all of these activities help you maintain bone tensile strength. Please tell me if I am not understanding this correctly. Should I introduce the strontium gradually, building up from one pill to two to three over a period of time or should I take one pill three times a day? Postmenopausal womens ovaries no longer produce estrogen, but small amounts of estrogen continue to be produced in many other parts of the body, and these small amounts of estrogen are essential for maintaining bone health. He is now telling his patients that once positive effects have been noted (say 3-6 months of 680 mg dose shown to be effective in the research) that they should drop this dose down to half this amount or even less. 2001 Sep;69(3):121-9. Strontium Boost can be taken with or without food (as it reads on the product label), but most folks take it right before bed on an empty stomach. First, does strontium expire? Alcohol. I have a history of IBS and have avoided gluten and used probiotics which has helped my GI tract to return to normal. My question: does Strontiums effect, in ranelate or citrate form, on osteoblasts and osteoclasts form the inference that fractures are reduced or has this been directly studied or proven perhaps even in the full studies which I have not read yet? I did return your call did you get the message I left for you? This is a 2007 dissertation paper I found on Europe PubMed Central. Will definitely not eat any more yogurt as that was just a sugar splurge. It's not known if strontium contained in dietary supplements has these effects. Medicines are intended to help us live longer and healthier, but taking medicines the wrong way or mixing certain drugs and supplements can be dangerous. 99% of Strontium is located in the teeth and bones where it promotes replication of preosteoblastic cells, which maintain bone health. PLEASE comment about this. Read more about Phytates & Calcium Absorption. A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. Bovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway. I have family sisters with ckd. When our nerves send a muscle cell a signal to fire, the muscle cell responds by allowing a flood of calcium to enter, and it is calciums entry into the muscle cell that initiates the cascade of reactions that result in making the muscle cell contract. It doesnt. Some foods provide feelings of satiety for a longer duration than . Expect results will be good. Our correspondence has been a total delight for me. Alternatively, some foods can interact with . any way if it does and i hope it will i want to thank and congratulate you on the Hi Robert, Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice. Theres a wee bit of disagreement as to how much somewhere between 40% and 50%. Once you know this, subtract this amount from 1,500 mg (if you are postmenopausal and not on bio-identical hormone replacement) or 1,200 if you are pre-menopause or postmenopausal and on BHRT. Because of my genetic inheritance, which includes faulty vitamin D receptors, I need even more vitamin D3 and therefore more K2 (D3 and K2 need to be in balance), so I take extra of these as well, also take some vitamin A (another fat-soluble nutrient that works with and must be in balance with vitamins D and K) and omega-3s (and try to eat salmon at least once a week). Mitigation of bone loss with ultrasound induced dynamic mechanical signals in an OVX induced rat model of osteopenia. There were a series of studies run as part of the Ryerson and McMaster University Strontium in Bone Research Study in Toronto, Canada, that confirm this, so I am giving you links to several of these papers here: https://www.ncbi.nlm.nih.gov/pubmed/22549020 https://www.ncbi.nlm.nih.gov/pubmed/26910208 https://www.ncbi.nlm.nih.gov/pubmed/24434614. If the blood clot lodges in the lungs, its called pulmonary embolism. Maybe its just me. Also, if your digestion is impaired or you are taking an acid-lowering drug, you will not be properly breaking down the proteins in your food, and undigested protein fragments that gain entry into your bloodstream can provoke many kinds of adverse reactions, including the skin symptoms you are experiencing. [Epub ahead of print]PMID: 22640372), My personal thoughts overall: Is this a test that those of us who take strontium citrate should be taking? I am concerned because I want to understand my osteoporosis treatment and make sure it meets your recommendations (like taking twice as much calcium as strontium possibly 1360 mg? if as much as 50% of that increase was due to strontiums larger size, then the women still gained 1.56% in BMD instead of losing 1-2% or more per year, so losing 3-6% of their BMD over the same time period. That being said, your note suggests to me that if you have not already had your vitamin D levels checked, you should do so! can I take just the AlgaeCal without Strontium? Lara. Today 2/27/13, I took her to the ER. Optimal intake is 1,2 1,500 mg per day for someone with osteoporosis. Please do not be overly concerned about having a calcium at high end of normal remember, you are still within the normal range. Youre so welcome. Has a horrible title, though Stay Young & Sexy with BHRT. Hi Lara, I am recently diagnosed with Oestopenea, I live in a part of world with poor health facilities and women health are completely neglected. AlgaeCal 2 had a positive MAPC of +2.79%. ? Strontium measurements were taken at the finger and ankle, representing primarily cortical and trabecular bone, respectively. You can get it at the following link. Please ask your doctor to check your thyroid hormone levels (T4, T3, rT3), and if you are hypothyroid, your levels of iodine and selenium should be evaluated. : Certain medications want you to either take or avoid taking on an empty stomach. Also, AlgaeCal Plus alone, or with Triple Power, which I definitely recommend especially for you because CKD indicates chronic inflammation, will support your bones ability to rebuild just a bit more slowly without Strontium Boost, which, as its name implies, boosts the rate at which new bone is formed. . Another fact: strontium is the only trace mineral present in human bone whose level in bone correlates with bone compressive strength, i.e., resistance to fracture. If high blood calcium levels are present, there are a number of tests she should consider and discuss with her endocrinologist these can all be found in 2nd edition of Your Bones in the 30 page long Lab Tests appendix. I find if I am good about taking my vitamin A and Triple Power, I am rarely sore the next day. Please feel free to contact our Bone Health Consultants 7 days a week at 1-800-820-0184 (USA & Canada, toll-free) or email [emailprotected] for more information and personalized support! If you do not object, I may use this information on some posts. I hope my full review of strontium will put to rest any concerns you might have regarding the potential for any adverse effects from the natural form of strontium, strontium citrate, which is what is present in Strontium Boost. Hope this helps, Lara, Hi so glad i found this site , my mom has exstensive bone marrow edema in 234and 5th matataresial bones in her foot also in the landrum of the foot shes 52 her bone density test came back low we are doing more blood work now the injury happened in october not sure how she has no fractures pain has now gone to her knees and she cant walk at all she always has poor eating habits smked and drinked most of her life nothing was helping the pain shes been on high calcium and vitamins for about a month now i started useing bone growth formula for her which she takes a strontium on an empty stomach so we tried Giving her a little more then 1000mg of it and its really gave her pain relief where no pain killer did we also started adding milk thistle and colostrum on an empty stomach first thing in the morning her insurance does not start till may 1st the problem is her xray on 11/19/12 the foot bones were all white next xray on 1/17/13 the bones seem to be turning black or OSTEONECEROIS MAYBE, ALMOST 90 DAYS TO GO IS IT TO RISKY TO WAIT? You could contact them and ask them what they do to ensure their products are free of heavy metals and other contaminants. As the daily dose of Strontium Boost is 4 capsules, it would be easy to cut down to half (2 caps) or 1/4 (1 capsule). Both the strontium and thecalcium supplements are absorbed in our gastrointestinal tracts using the same mechanism. Reviewed in the United . In addition, Algaecal suggests taking Strontium Boost along with Algaecal Plus. Some other things SCW might consider and discuss with her doctor: I am wondering, how much calcium is SCW taking? If she is consuming 680 mg elemental strontium daily, then she should be getting at least twice that amount (1360 mg) of calcium each day from her diet and supplements. Firstly sincere thanks and appreciation for the contents of this blog. Vitamin D increases our bodys ability to absorb calcium; vitamin K2 activates the proteins responsible for putting calcium into bone (osteocalcin) and keeping it OUT of arteries, kidneys, breasts. https://www.ncbi.nlm.nih.gov/pubmed/?term=15336592 Plus, strontium is mainly incorporated onto the crystal surface of newly formed (trabecular) bone where one ion of strontium replaces less than one calcium ion out of 10. People with bleeding disorders: NAC can slow blood clotting.Don't take it if you have a bleeding disorder such as hemophilia or Von Willebrand disease. From Laras Comment at bottom of: Strontium Side Effects are Overblown Get the Facts: Strontium is almost twice as large as calcium, and its larger size does affect DXA readings. I had been building bone for several years; improvement was consistent but slow. Hello Cinzia, You recently stated the following: Strontium, like calcium, incorporates into both trabecular and cortical bone, but strontium deposits almost entirely into newly forming trabecular bone, with one strontium ion substituting for less than one calcium ion out of 10 in the bone matrix. I would be really interested to know 1) the exact amount that ends up as cortical bone and its incidence in making it weaker 2) to view the studies highlighting the assimilation of Strontium as trabecular bone. Is because food and some drinks can affect the way these medicines work same mechanism suggests strontium! Target of therapy for approximately 30 % of strontium is located in the lungs, its called pulmonary embolism provide... A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss used. The AlgaeCal that you recommend special form of strontium called strontium ranelate can increase bone formation and bone. 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